What is the turnover number of an enzyme, and how does it differ from the specific activity? Why does this value not change as an enzyme is purified? How fast is the maximum turnover number of an enzyme and what limits the magnitude of this number?

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What is the turnover number of an enzyme, and how does it differ from the specific activity? Why does this value not change as an enzyme is purified? How fast is the maximum turnover number of an enzyme and what limits the magnitude of this number?



The turnover number is the max number of molecules of substrate that an enzyme can convert to product per catalytic site per unit of time.

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