Law of Conservation of Mass Mass is not created nor destroyed during an ordinary chemical reaction. (CH4 + 2O2 = CO2 + H2O (Mass Reactants equal Mass Products)) Exceptions include Nuclear Reactions (E =mc^2). Law of Conservation of Energy Energy in the universe is conserved but changes form. Law of Multiple Proportions Two different elements can form more than one compound (NO, NO2, N2O2). Law of Definite Composition Using the atomic mass on the Periodic Table, the ratio of Mg to O is 24:16. No matter how much of the compound you have, the ratio will always be 24:16.