Explain the activities at the replication fork?

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Explain the activities at the replication fork?



The enzyme DNA helicase opens up a replication fork, where synthesis of new daughter DNA strands can begin. The overall direction of movement of the replication fork matches that of the continuous 5'→3' synthesis of one daughter DNA strand, the leading strand. Replication is semi-discontinuous because the lagging strand, which is synthesized in the opposite direction, is built up in pieces (Okazaki fragments, shown here as fragments A, B, and C) that will later be stitched together by a DNA ligase.

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