What is the Monroe Kellie Hypothesis and why is this important to your patient with increased intracranial pressure?

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What is the Monroe Kellie Hypothesis and why is this important to your patient with increased intracranial pressure? 




Answer: In the adult, the rigid cranial cavity created by the skull is normally filled to capacity with three essentially non-compressible elements: the brain (80%), cerebrospinal fluid (8%) and blood (12%). A state of dynamic equilibrium exists; if the volume of any of the three components increases, the volume of the others must decrease to maintain normal pressures within the cranial cavity. This is known as the Monro-Kellie hypothesis.

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