Describe the following mechanisms of response to foreign materials in the human body. A) The antigen-antibody response to a skin graft from another person. B) The reactions of the body leading to inflammation of a wound infected by bacteria.

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Describe the following mechanisms of response to foreign materials in the human body. 

A) The antigen-antibody response to a skin graft from another person.  

B) The reactions of the body leading to inflammation of a wound infected by bacteria.


A) The antigen recognizes the new skin as foreign. Then it is rejected by the immune system. The antigens surface to the graft cells. Then they stimulate antibody production and T cell production. B Lymphocytes are turned into plasma cells which synthesizes antibodies. The antibodies circulate to the sites needed and precipitate antigens and/or complex. The antibodies make the antigens susceptible to phagocytosis by WBCs. Then the antibodies specify and it fights off the graft and other infections that come with it.

B)When injured, mast cells release their histamine which triggers dilation and it increases permeability of nearby capillaries. Activated macrophages and other cells discharge additional signals that further promote blood flow. The increase in blood supply causes the redness and heat typical inflammation to occur.

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